aboutsummaryrefslogtreecommitdiffstats
path: root/python/tests/files/nature_article.html
blob: 177da83cd87a8172bbc994027b9932f61cea4d2d (plain)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
1001
1002
1003
1004
1005
1006
1007
1008
1009
1010
1011
1012
1013
1014
1015
1016
1017
1018
1019
1020
1021
1022
1023
1024
1025
1026
1027
1028
1029
1030
1031
1032
1033
1034
1035
1036
1037
1038
1039
1040
1041
1042
1043
1044
1045
1046
1047
1048
1049
1050
1051
1052
1053
1054
1055
1056
1057
1058
1059
1060
1061
1062
1063
1064
1065
1066
1067
1068
1069
1070
1071
1072
1073
1074
1075
1076
1077
1078
1079
1080
1081
1082
1083
1084
1085
1086
1087
1088
1089
1090
1091
1092
1093
1094
1095
1096
1097
1098
1099
1100
1101
1102
1103
1104
1105
1106
1107
1108
1109
1110
1111
1112
1113
1114
1115
1116
1117
1118
1119
1120
1121
1122
1123
1124
1125
1126
1127
1128
1129
1130
1131
1132
1133
1134
1135
1136
1137
1138
1139
1140
1141
1142
1143
1144
1145
1146
1147
1148
1149
1150
1151
1152
1153
1154
1155
1156
1157
1158
1159
1160
1161
1162
1163
1164
1165
1166
1167
1168
1169
1170
1171
1172
1173
1174
1175
1176
1177
1178
1179
1180
1181
1182
1183
1184
1185
1186
1187
1188
1189
1190
1191
1192
1193
1194
1195
1196
1197
1198
1199
1200
1201
1202
1203
1204
1205
1206
1207
1208
1209
1210
1211
1212
1213
1214
1215
1216
1217
1218
1219
1220
1221
1222
1223
1224
1225
1226
1227
1228
1229
1230
1231
1232
1233
1234
1235
1236
1237
1238
1239
1240
1241
1242
1243
1244
1245
1246
1247
1248
1249
1250
1251
1252
1253
1254
1255
1256
1257
1258
1259
1260
1261
1262
1263
1264
1265
1266
1267
1268
1269
1270
1271
1272
1273
1274
1275
1276
1277
1278
1279
1280
1281
1282
1283
1284
1285
1286
1287
1288
1289
1290
1291
1292
1293
1294
1295
1296
1297
1298
1299
1300
1301
1302
1303
1304
1305
1306
1307
1308
1309
1310
1311
1312
1313
1314
1315
1316
1317
1318
1319
1320
1321
1322
1323
1324
1325
1326
1327
1328
1329
1330
1331
1332
1333
1334
1335
1336
1337
1338
1339
1340
1341
1342
1343
1344
1345
1346
1347
1348
1349
1350
1351
1352
1353
1354
1355
1356
1357
1358
1359
1360
1361
1362
1363
1364
1365
1366
1367
1368
1369
1370
1371
1372
1373
1374
1375
1376
1377
1378
1379








<!DOCTYPE html>
<html lang="en" class="grade-c">
<head>
    <meta charset="utf-8">
<link rel="dns-prefetch" href="//ajax.googleapis.com"/>
<link rel="dns-prefetch" href="//fonts.googleapis.com"/>
<link rel="dns-prefetch" href="//fonts.gstatic.com"/>
<meta http-equiv="X-UA-Compatible" content="IE=edge">
<meta name="viewport" content="width=device-width, initial-scale=1.0, shrink-to-fit=no">

    <title>More than 100 scientific journals have disappeared from the Internet</title>
    <meta name="description" content="Researchers have identified dozens of open-access journals that went offline between 2000 and 2019, and hundreds more that could be at risk."/>
    <meta property="og:url" content="https://www.nature.com/articles/d41586-020-02610-z"/>
    <meta property="og:type" content="article"/>
    <meta property="og:title" content="More than 100 scientific journals have disappeared from the Internet"/>
    <meta property="og:description" content="Researchers have identified dozens of open-access journals that went offline between 2000 and 2019, and hundreds more that could be at risk."/>
    <meta property="og:image"
          content="https://media.nature.com/lw1024/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_18365322.jpg"/>
    <meta name="twitter:card" content="summary_large_image"/>
    <meta name="twitter:site" content="@nature"/>
    <meta name="twitter:title" content="More than 100 scientific journals have disappeared from the Internet"/>
    <meta name="twitter:description" content="Researchers have identified dozens of open-access journals that went offline between 2000 and 2019, and hundreds more that could be at risk."/>
    <meta name="twitter:image"
          content="https://media.nature.com/lw1024/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_18365322.jpg"/>
    

    <meta name="journal_id" content="41586"/>

    <meta name="dc.title" content="More than 100 scientific journals have disappeared from the Internet"/>

    <meta name="dc.source" content="Nature 2020"/>

    <meta name="dc.format" content="text/html"/>

    <meta name="dc.publisher" content="Nature Publishing Group"/>

    <meta name="dc.date" content="2020-09-10"/>

    <meta name="dc.type" content="News"/>

    <meta name="dc.language" content="En"/>

    <meta name="dc.copyright" content="2020 Nature"/>

    <meta name="dc.rightsAgent" content="journalpermissions@springernature.com"/>

    <meta name="dc.description" content="Researchers have identified dozens of open-access journals that went offline between 2000 and 2019, and hundreds more that could be at risk.  Researchers have identified dozens of open-access journals that went offline between 2000 and 2019, and hundreds more that could be at risk."/>

    <meta name="prism.publicationName" content="Nature"/>

    <meta name="prism.publicationDate" content="2020-09-10"/>

    <meta name="prism.section" content="News"/>

    <meta name="prism.startingPage" content=""/>

    <meta name="prism.endingPage" content=""/>

    <meta name="prism.copyright" content="2020 Nature"/>

    <meta name="prism.rightsAgent" content="journalpermissions@springernature.com"/>

    <meta name="prism.url" content="https://www.nature.com/articles/d41586-020-02610-z"/>

    <meta name="prism.doi" content="doi:10.1038/d41586-020-02610-z"/>

    <meta name="dc.identifier" content="doi:10.1038/d41586-020-02610-z"/>

    <meta name="DOI" content="10.1038/d41586-020-02610-z"/>

    <meta name="description" content="Researchers have identified dozens of open-access journals that went offline between 2000 and 2019, and hundreds more that could be at risk.  Researchers have identified dozens of open-access journals that went offline between 2000 and 2019, and hundreds more that could be at risk."/>

    <meta name="dc.creator" content="Diana Kwon"/>

    <meta name="dc.subject" content="Publishing"/>



<script>(function(e){var t=e.documentElement,n=e.implementation;t.className='js';if(n&&n.hasFeature('http://www.w3.org/TR/SVG11/feature#Image','1.1')){t.className+=' svg'}})(document)</script>
<link rel="stylesheet" href="/static/css/mosaic-grade-c.26f07b2f11.css">

<link rel="stylesheet" class="js-ctm" href="/static/css/magazine-mosaic-150.7f46c29843.css" media="only screen, print and (-webkit-min-device-pixel-ratio:0) and (min-color-index:0), (-ms-high-contrast: none), only all and (min--moz-device-pixel-ratio:0) and (min-resolution: 3e1dpcm)">


    <style>
        .c-header--brand-border {
            border-bottom: 5px solid #000;
        }
    </style>

<link rel="apple-touch-icon" sizes="180x180" href=/static/images/favicons/nature/apple-touch-icon.f39cb19454.png>
<link rel="icon" type="image/png" sizes="32x32" href=/static/images/favicons/nature/favicon-32x32.3fe59ece92.png>
<link rel="icon" type="image/png" sizes="16x16" href=/static/images/favicons/nature/favicon-16x16.951651ab72.png>
<link rel="manifest" href=/static/manifest.1a481c42b1.json>
<link rel="mask-icon" href=/static/images/favicons/nature/safari-pinned-tab.69bff48fe6.svg color="#000000">
<link rel="shortcut icon" href=/static/images/favicons/nature/favicon.62367f778b.ico>
<meta name="msapplication-TileColor" content="#000000">
<meta name="msapplication-config" content=/static/browserconfig.e35b3b052c.xml>
<meta name="theme-color" content="#000000">
<meta name="application-name" content="Nature">

<link rel="search" href="http://www.nature.com/search">
<link rel="search" href="http://www.nature.com/opensearch/opensearch.xml" type="application/opensearchdescription+xml" title="nature.com">
<link rel="search" href="http://www.nature.com/opensearch/request" type="application/sru+xml" title="nature.com">

    <meta name="WT.cg_s" content="News"/>
    <meta name="WT.z_cg_type" content="News"/>
    <meta name="WT.page_categorisation" content="Article page"/>
    <meta name="WT.z_subject_term" content="Publishing"/>

<meta name="WT.template" content="oscar"/>
<meta name="WT.cg_n" content="Nature"/>
<meta name="dc.rights" content="©2020 Macmillan Publishers Limited. All Rights Reserved."/>
<meta name="WT.z_bandiera_abtest" content="a"/>

    <script data-test="dataLayer">
        dataLayer = [{"content":{"category":{"contentType":"news","legacy":{"webtrendsPrimaryArticleType":"news","webtrendsSubjectTerms":"publishing","webtrendsContentCategory":null,"webtrendsContentCollection":null,"webtrendsContentGroup":"Nature","webtrendsContentGroupType":null,"webtrendsContentSubGroup":"News"}},"article":{"doi":"10.1038/d41586-020-02610-z"},"attributes":{"cms":"core media","deliveryPlatform":"oscar","copyright":{"open":false,"legacy":{"webtrendsLicenceType":null}}},"contentInfo":{"authors":["Diana Kwon"],"publishedAt":1599696000,"publishedAtString":"2020-09-10","title":"More than 100 scientific journals have disappeared from the Internet","legacy":null,"publishedAtTime":null,"documentType":"aplusplus"},"journal":{"pcode":"nature","title":"nature","volume":null,"issue":null},"authorization":{"status":true},"features":[{"name":"furtherReadingSection","present":false}],"collection":null},"page":{"category":{"pageType":"article"},"attributes":{"template":"magazine mosaic","featureFlags":[{"name":"ab_test_news_feature","active":false}]},"search":null},"privacy":{},"version":"1.0.0","product":null,"session":null,"user":null,"backHalfContent":false}];
</script>

<script>
    (function() {
        function deleteCookie (name, domain) {
            document.cookie = encodeURIComponent(name) +
                    '=' +
                    ';path=/' +
                    ';domain=' + domain +
                    ';expires=Thu, 01 Jan 1970 00:00:00 GMT';
        }

        var consentCookieParts = ('; ' + document.cookie).split('; OptanonConsent=');

        if (consentCookieParts.length > 1) {
            consentCookieParts.shift(); // remove redundant first part from the split array

            // onetrust can set the same cookie multiple times with different domain specificities
            for (let i=0; i<consentCookieParts.length; i++) {
                var otCookieGroups = consentCookieParts[i].split('&groups=').pop().split('&').shift();

                if (otCookieGroups.indexOf('C0001') === -1) {
                    deleteCookie('OptanonConsent', 'nature.com');
                    deleteCookie('OptanonAlertBoxClosed', 'nature.com');
                }
            }
        }
    })();
</script>

<script>
    (function(w,d,t) {
        function cc() {
            var h = w.location.hostname;
            if (h.indexOf('preview-www.nature.com') > -1) return;

            var e = d.createElement(t),
                s = d.getElementsByTagName(t)[0];

            if (h.indexOf('nature.com') > -1) {
                e.src = 'https://cdn.cookielaw.org/scripttemplates/otSDKStub.js';
                e.setAttribute('data-domain-script', '83f2c78a-6cbc-4d1a-9088-3f8e8c4c7460');
            } else {
                e.src = '/static/js/cookie-consent-bundle.9d49adbc02.js';
                e.setAttribute('data-consent', h);
            }
            s.parentNode.insertBefore(e, s);
        }

        !!w.google_tag_manager ? cc() : window.addEventListener('gtm_loaded', function() {cc()});
    })(window,document,'script');
</script>
<script>
    function OptanonWrapper() {
        window.dataLayer.push({event:'OneTrustGroupsUpdated'});
        document.activeElement.blur();
    }
</script>


<script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':
        new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],
    j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src=
    'https://www.googletagmanager.com/gtm.js?id='+i+dl;

    
    j.addEventListener('load', function() {
    var _ge = new CustomEvent('gtm_loaded', { bubbles: true });
    d.dispatchEvent(_ge);
    });

    f.parentNode.insertBefore(j,f);
})(window,document,'script','dataLayer','GTM-NWDMT9Q');</script>



</head>
<body>
    
    
        
<div role="banner" class="position-relative cleared z-index-50 background-white" data-test="top-containers">
    
    
        <a class="c-skip-link u-hide-print" href="#content">Skip to main content</a>
    

    
        

        

        <aside class="c-ad c-ad--728x90">
            <div class="c-ad__inner" data-container-type="banner-advert">
                <p class="c-ad__label">Advertisement</p>
                    
            
            
                <div id="article-doubleclickad-container">
    <div id="div-gpt-ad-top-1"
         class="div-gpt-ad advert leaderboard js-ad text-center hide-print grade-c-hide"
         data-ad-type="top"
         data-gpt-unitpath="/285/nature.com/article"
         data-gpt-sizes="728x90"
         data-gpt-targeting="type=article;pos=top;artid=d41586-020-02610-z;doi=10.1038/d41586-020-02610-z;subjmeta=479,648,706;kwrd=Publishing">
        <noscript>
            <a href="//pubads.g.doubleclick.net/gampad/jump?iu=/285/nature.com/article&amp;sz=728x90&amp;c=766965215&amp;t=pos%3Dtop%26type%3Darticle%26artid%3Dd41586-020-02610-z%26doi%3D10.1038/d41586-020-02610-z%26subjmeta%3D479,648,706%26kwrd%3DPublishing">
                <img data-test="gpt-advert-fallback-img"
                     src="//pubads.g.doubleclick.net/gampad/ad?iu=/285/nature.com/article&amp;sz=728x90&amp;c=766965215&amp;t=pos%3Dtop%26type%3Darticle%26artid%3Dd41586-020-02610-z%26doi%3D10.1038/d41586-020-02610-z%26subjmeta%3D479,648,706%26kwrd%3DPublishing"
                     alt="Advertisement"
                     width="728"
                     height="90"></a>
        </noscript>
    </div>
</div>

            
            
        
            </div>
        </aside>
    

    

    
        <div class="c-grade-c-banner u-hide">
            <div class="c-grade-c-banner__container">
                
        <p>Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
            the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
            Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
            and JavaScript.</p>
    
            </div>
        </div>
    


    
    <header class="c-header c-header--brand-border" id="header" data-header>
        <div class="c-header__row-border">
            <div class="c-header__container">
                <div class="c-header__layout">
                    <a href="/nature"
                       data-track="click" data-track-action="home" data-track-category="nature-150-split-header" data-track-label="image">
                        <picture class="c-header__logo">
                            <source srcset="//media.springernature.com/full/nature-cms/uploads/product/nature/header-86f1267ea01eccd46b530284be10585e.svg" media="(min-width: 769px)">
                            <img src="//media.springernature.com/full/nature-cms/uploads/product/nature/header-86f1267ea01eccd46b530284be10585e.svg" alt="Nature">
                        </picture>
                    </a>
                    <div class="c-header__layout">
                        
                            <div class="c-header__site-navigation c-header__site-navigation--show-at-md"
                                 data-test="siteindex-link">
                                <a class="c-header__link" href="https://www.nature.com/siteindex"
                                   data-track="click" data-track-category="nature-150-split-header" data-track-action="open nature research index" data-track-label="link">
                                    <span>View all Nature Research journals</span>
                                </a>
                            </div>
                        
                        <div class="c-header__site-navigation c-header__site-navigation--border">
                            <a class="c-header__link"
                               href="#search-menu"
                               data-header-expander
                               data-test="search-link" data-track="click" data-track-category="nature-150-split-header" data-track-action="open search tray" data-track-label="button">
                                <span>Search</span><svg role="img" aria-hidden="true" focusable="false" height="22" width="22" viewBox="0 0 18 18" xmlns="http://www.w3.org/2000/svg"><path d="M16.48 15.455c.283.282.29.749.007 1.032a.738.738 0 01-1.032-.007l-3.045-3.044a7 7 0 111.026-1.026zM8 14A6 6 0 108 2a6 6 0 000 12z"/></svg>
                            </a>
                            <a href="/nams/svc/myaccount"
    id="my-account"
    class="c-header__link placeholder"
    data-test="login-link" data-track="click" data-track-action="my account" data-track-category="nature-150-split-header" data-track-label="link">
    <span>My Account</span><svg role="img" aria-hidden="true" focusable="false" height="22" width="22" viewBox="0 0 18 18" xmlns="http://www.w3.org/2000/svg"><path d="M10.238 16.905a7.96 7.96 0 003.53-1.48c-.874-2.514-2.065-3.936-3.768-4.319V9.83a3.001 3.001 0 10-2 0v1.277c-1.703.383-2.894 1.805-3.767 4.319A7.96 7.96 0 009 17c.419 0 .832-.032 1.238-.095zm4.342-2.172a8 8 0 10-11.16 0c.757-2.017 1.84-3.608 3.49-4.322a4 4 0 114.182 0c1.649.714 2.731 2.305 3.488 4.322zM9 18A9 9 0 119 0a9 9 0 010 18z" fill="#333" fill-rule="evenodd"/></svg>
</a>
<a href="https://idp.nature.com/authorize/natureuser?client_id&#x3D;grover&amp;redirect_uri&#x3D;https%3A%2F%2Fwww.nature.com%2Farticles%2Fd41586-020-02610-z"
    id="login-button"
    style="display: none;"
    class="c-header__link placeholder"
    data-test="login-link" data-track="click" data-track-action="login" data-track-category="nature-150-split-header" data-track-label="link">
    <span>Login</span><svg role="img" aria-hidden="true" focusable="false" height="22" width="22" viewBox="0 0 18 18" xmlns="http://www.w3.org/2000/svg"><path d="M10.238 16.905a7.96 7.96 0 003.53-1.48c-.874-2.514-2.065-3.936-3.768-4.319V9.83a3.001 3.001 0 10-2 0v1.277c-1.703.383-2.894 1.805-3.767 4.319A7.96 7.96 0 009 17c.419 0 .832-.032 1.238-.095zm4.342-2.172a8 8 0 10-11.16 0c.757-2.017 1.84-3.608 3.49-4.322a4 4 0 114.182 0c1.649.714 2.731 2.305 3.488 4.322zM9 18A9 9 0 119 0a9 9 0 010 18z" fill="#333" fill-rule="evenodd"/></svg>
</a>

                        </div>
                    </div>
                </div>
            </div>
        </div>
        
            <div class="c-header__container" data-test="c-header__container">
                <ul class="c-header__menu">
                    
                        <li class="c-header__item" data-test="explore-content-button">
                            <a href="#explore"
                               class="c-header__link c-header__link--dropdown"
                               data-header-expander
                               data-test="menu-button"
                               data-track="click" data-track-category="nature-150-split-header" data-track-action="open explore expander" data-track-label="button">
                                <span>Explore <span class="c-header__show-text">our content</span></span><svg role="img" aria-hidden="true" focusable="false" height="16" viewBox="0 0 16 16" width="16" xmlns="http://www.w3.org/2000/svg"><path d="m5.58578644 3-3.29289322-3.29289322c-.39052429-.39052429-.39052429-1.02368927 0-1.41421356s1.02368927-.39052429 1.41421356 0l4 4c.39052429.39052429.39052429 1.02368927 0 1.41421356l-4 4c-.39052429.39052429-1.02368927.39052429-1.41421356 0s-.39052429-1.02368927 0-1.41421356z" transform="matrix(0 1 -1 0 11 3)"/></svg>
                            </a>
                        </li>
                    
                    <li class="c-header__item">
                        <a href="#journal-info"
                           class="c-header__link c-header__link--dropdown"
                           data-header-expander
                           data-test="menu-button"
                           data-track="click" data-track-category="nature-150-split-header" data-track-action="open journal information expander" data-track-label="button">
                            <span>Journal info<span class="c-header__show-text">rmation</span></span><svg role="img" aria-hidden="true" focusable="false" height="16" viewBox="0 0 16 16" width="16" xmlns="http://www.w3.org/2000/svg"><path d="m5.58578644 3-3.29289322-3.29289322c-.39052429-.39052429-.39052429-1.02368927 0-1.41421356s1.02368927-.39052429 1.41421356 0l4 4c.39052429.39052429.39052429 1.02368927 0 1.41421356l-4 4c-.39052429.39052429-1.02368927.39052429-1.41421356 0s-.39052429-1.02368927 0-1.41421356z" transform="matrix(0 1 -1 0 11 3)"/></svg>
                        </a>
                    </li>
                    
                        <li class="c-header__item c-header__item--pipe">
                            <a class="c-header__link"
                               href="https://www.nature.com/nature/subscribe"
                               data-track="click"
                               data-track-action="subscribe"
                               data-track-category="nature-150-split-header"
                               data-track-label="link">
                                <span>Subscribe</span>
                            </a>
                        </li>
                    
                </ul>
            </div>
        
    </header>

    
        
    
    <div class="u-mb-16">
        <div class="u-container">
            <ol class="c-breadcrumbs">
            <li class="c-breadcrumbs__item" id="breadcrumb0"
                        itemscope="itemscope" itemtype="http://data-vocabulary.org/Breadcrumb" itemref="breadcrumb1"><a class="c-breadcrumbs__link"
                            href="/"
                            itemprop="url"
                            data-track="click" data-track-action="breadcrumb" data-track-category="header" data-track-label="link:nature"><span itemprop="title">nature</span></a><svg class="c-icon c-breadcrumbs__chevron" aria-hidden="true" focusable="false" height="10" viewBox="0 0 10 10" width="10" xmlns="http://www.w3.org/2000/svg"><path d="m5.96738168 4.70639573 2.39518594-2.41447274c.37913917-.38219212.98637524-.38972225 1.35419292-.01894278.37750606.38054586.37784436.99719163-.00013556 1.37821513l-4.03074001 4.06319683c-.37758093.38062133-.98937525.38100976-1.367372-.00003075l-4.03091981-4.06337806c-.37759778-.38063832-.38381821-.99150444-.01600053-1.3622839.37750607-.38054587.98772445-.38240057 1.37006824.00302197l2.39538588 2.4146743.96295325.98624457z" fill="#666" fill-rule="evenodd" transform="matrix(0 -1 1 0 0 10)"/></svg></li><li class="c-breadcrumbs__item" id="breadcrumb1"
                        itemscope="itemscope" itemtype="http://data-vocabulary.org/Breadcrumb" itemref="breadcrumb2"><a class="c-breadcrumbs__link"
                            href="/nature/articles?type&#x3D;news"
                            itemprop="url"
                            data-track="click" data-track-action="breadcrumb" data-track-category="header" data-track-label="link:news"><span itemprop="title">news</span></a><svg class="c-icon c-breadcrumbs__chevron" aria-hidden="true" focusable="false" height="10" viewBox="0 0 10 10" width="10" xmlns="http://www.w3.org/2000/svg"><path d="m5.96738168 4.70639573 2.39518594-2.41447274c.37913917-.38219212.98637524-.38972225 1.35419292-.01894278.37750606.38054586.37784436.99719163-.00013556 1.37821513l-4.03074001 4.06319683c-.37758093.38062133-.98937525.38100976-1.367372-.00003075l-4.03091981-4.06337806c-.37759778-.38063832-.38381821-.99150444-.01600053-1.3622839.37750607-.38054587.98772445-.38240057 1.37006824.00302197l2.39538588 2.4146743.96295325.98624457z" fill="#666" fill-rule="evenodd" transform="matrix(0 -1 1 0 0 10)"/></svg></li><li class="c-breadcrumbs__item" id="breadcrumb2"
                        itemscope="itemscope" itemtype="http://data-vocabulary.org/Breadcrumb" itemref="breadcrumb3"><span itemprop="title">article</span></li>
            </ol>
        </div>
    </div>
    

    
    
    

</div>

    
    <div  id="content" class="article-page position-relative z-index-1">
    <section class="container highlight-container article-page--news container-with-gap">
        <article class="article-item article-item--open" itemscope="" itemtype="http://schema.org/NewsArticle"
         data-track-component="news">
    <div class="container cleared container-type-article" data-container-type="article" itemprop="articleBody">
        <div class="content position-relative cleared clear mq1200-padded" data-component="article-container"
             role="main">
            <header class="article-item__header clear cleared pull--both">
                <div class="article__type">NEWS
                    <div class="ml10 article__date">
                        <time itemprop="datePublished">10 September 2020</time>
                    </div>
                </div>
                
                <div class="clear cleared"></div>
                <h1 class="article-item__title serif" itemprop="headline">More than 100 scientific journals have disappeared from the Internet</h1>
                
                <div class="article-item__teaser-text serif">
                    Researchers have identified dozens of open-access journals that went offline between 2000 and 2019, and hundreds more that could be at risk.
                </div>
            </header>

            <div class="clear cleared"></div>
            
                <div class="bordered-container clear cleared pull--both">
                    <div id="author-affiliations" class="tab-group text14" role="tablist" data-test="author-affiliations" data-tab-group>
    <div class="cleared">
        
            <div id="author-affiliation-news-0" class="tab-box js-box-wrapper">
                <h3 id="author-affiliation-news-0-head" data-track="click" data-track-label="view author info" class="sans-serif strong tab tab-skin ma0" role="tab"
                    aria-controls="author-affiliation-news-0-content" data-tooltip="Show author information">
                    Diana Kwon
                </h3>
                <div id="author-affiliation-news-0-content" class="tab-content pin-right grid grid-12 last"
                     role="tabpanel">
                    <div class="pa10" aria-labelledby="author-affiliation-news-0-head">
                        <div class="clear cleared">
                            
                                
                                    <div class="align-left">
                                        <h4 class="sans-serif">Search for this author in:</h4>
                                        <ul class="ma0 clean-list">
                                            <li class="strong"><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd&#x3D;search&amp;term&#x3D;%22Diana%2BKwon%22" data-track="click" data-track-label="Pub Med" >Pub Med</a></li>
                                        
                                            <li class="strong"><a href="https://www.nature.com/search?order&#x3D;date_desc&amp;q&#x3D;%22Diana%2BKwon%22" data-track="click" data-track-label="Nature.com" >Nature.com</a></li>
                                        
                                            <li class="strong"><a href="https://scholar.google.co.uk/scholar?as_q&#x3D;&amp;btnG&#x3D;Search+Scholar&amp;as_sauthors&#x3D;%22Diana%2BKwon%22" data-track="click" data-track-label="Google Scholar" >Google Scholar</a></li>
                                        </ul>
                                    </div>
                                
                            
                            
                        </div>
                    </div>
                </div>
            </div>
        
    </div>
</div>

                </div>
            
            <div class="clear cleared pull--both">
                <ul class="social clean-list inline-list hide-print">
    <li class="mr10">
        <a class="icon--inline inline-block" data-track="click" data-track-action="twitter" data-track-category="social" data-track-label="10.1038/d41586-020-02610-z" href="https://twitter.com/intent/tweet?text=More+than+100+scientific+journals+have+disappeared+from+the+Internet&url=https%3A%2F%2Fwww.nature.com%2Farticles%2Fd41586-020-02610-z">
            <?xml version="1.0" encoding="UTF-8" standalone="no"?>
            <svg role="img" focusable="false" viewBox="0 0 30 30" version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
                <title>Share on Twitter</title>
                <desc>Share on Twitter</desc>
                <defs></defs>
                <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd">
                    <g>
                        <polygon points="0 0 30 0 30 30 0 30"></polygon>
                        <path d="M20.8125,11.4875 C21.42,11.10375 21.8875,10.49625 22.105,9.7725 C21.5375,10.1275 20.90875,10.385 20.23875,10.5225 C19.70625,9.9225 18.9425,9.545 18.0975,9.545 C16.475,9.545 15.16,10.9325 15.16,12.6425 C15.16,12.885 15.185,13.1225 15.235,13.3475 C12.7975,13.2175 10.63125,11.985 9.1825,10.11 C8.93,10.56875 8.785,11.10125 8.785,11.66875 C8.785,12.74375 9.30375,13.69125 10.09125,14.2475 C9.61125,14.23125 9.1575,14.09 8.76125,13.86 L8.76125,13.8975 C8.76125,15.3975 9.77375,16.65125 11.11875,16.935 C10.87125,17.0075 10.6125,17.04375 10.34375,17.04375 C10.15625,17.04375 9.96875,17.025 9.79125,16.98875 C10.16625,18.22125 11.24875,19.11875 12.535,19.1425 C11.52875,19.97375 10.2625,20.4675 8.885,20.4675 C8.6475,20.4675 8.415,20.455 8.185,20.42625 C9.485,21.30375 11.02875,21.81625 12.6875,21.81625 C18.09,21.81625 21.04375,17.095 21.04375,13.00125 L21.03625,12.60125 C21.61125,12.16375 22.11125,11.6175 22.50125,10.99625 C21.97375,11.2425 21.4075,11.40875 20.81375,11.48375 L20.8125,11.4875 Z"
                              fill-rule="nonzero"></path>
                    </g>
                </g>
            </svg>
        </a>
    </li>
    <li class="mr10">
        <a class="icon--inline inline-block" data-track="click" data-track-action="facebook" data-track-category="social" data-track-label="10.1038/d41586-020-02610-z" href="http://www.facebook.com/sharer.php?u=https%3A%2F%2Fwww.nature.com%2Farticles%2Fd41586-020-02610-z">
            <?xml version="1.0" encoding="UTF-8" standalone="no"?>
            <svg role="img" focusable="false" viewBox="0 0 30 30" version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
                <title>Share on Facebook</title>
                <desc>Share on Facebook</desc>
                <defs></defs>
                <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd">
                    <g>
                        <polygon points="0 0 30 0 30 30 0 30"></polygon>
                        <path d="M15.89625,22.8625 L12.57125,22.8625 L12.57125,15.02125 L10.90875,15.02125 L10.90875,12.31875 L12.57125,12.31875 L12.57125,10.69625 C12.57125,8.4925 13.50875,7.18 16.175,7.18 L18.39375,7.18 L18.39375,9.8825 L17.00625,9.8825 C15.96875,9.8825 15.9,10.26 15.9,10.965 L15.895,12.3175 L18.4075,12.3175 L18.115,15.02 L15.89625,15.02 L15.89625,22.8625 Z"
                              fill-rule="nonzero"></path>
                    </g>
                </g>
            </svg>
        </a>
    </li>
    <li class="mr10">
        <a class="icon--inline inline-block" data-track="click" data-track-action="email" data-track-category="social" data-track-label="10.1038/d41586-020-02610-z" href="mailto:?subject=More than 100 scientific journals have disappeared from the Internet&body=https%3A%2F%2Fwww.nature.com%2Farticles%2Fd41586-020-02610-z">
            <?xml version="1.0" encoding="UTF-8" standalone="no"?>
            <svg role="img" focusable="false" viewBox="0 0 30 30" version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
                <title>Share via E-Mail</title>
                <desc>Share via E-Mail</desc>
                <defs></defs>
                <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd">
                    <g>
                        <g>
                            <polygon points="0 0 30 0 30 30 0 30"></polygon>
                            <path d="M15,15.3269887 L10.6248577,11.9177869 C10.4236021,11.7609644 10.1299323,11.7927468 9.96892789,11.988775 C9.80792343,12.1848031 9.84055341,12.4708451 10.041809,12.6276676 L14.7012493,16.2584003 C14.8680779,16.3940555 15.1152493,16.4013884 15.2915244,16.2640313 C15.2939898,16.2622325 15.2963784,16.2603294 15.2987507,16.2584003 L19.958191,12.6276676 C20.1594466,12.4708451 20.1920766,12.1848031 20.0310721,11.988775 C19.8700677,11.7927468 19.5763979,11.7609644 19.3751423,11.9177869 L15,15.3269887 Z M9,10 L21,10 C21.5522847,10 22,10.4477153 22,11 L22,19 C22,19.5522847 21.5522847,20 21,20 L9,20 C8.44771525,20 8,19.5522847 8,19 L8,11 C8,10.4477153 8.44771525,10 9,10 Z"></path>
                        </g>
                    </g>
                </g>
            </svg>
        </a>
    </li>
</ul>

            </div>
            
            
            
            
            <div class="align-left">
                
                    <div class="article__body serif cleared">
                        <p>Scholarly journals are supposed to provide a lasting record of science. But over the past two decades, 176 open-access journals — and many of the papers published in them — have disappeared from the Internet, according to an analysis published on 27 August<sup><a href="#ref-CR1" data-track="click" data-action="anchor-link" data-track-label="go to reference" data-track-category="references">1</a></sup>.</p><p>“There shouldn’t really be any decay or loss in scientific publications, particularly those that have been open on the web,” says Mikael Laakso, an information scientist at the Hanken School of Economics in Helsinki, and a co-author of the study, which was posted on the arXiv preprint server. He and his colleagues identified 176 titles whose online presence vanished between 2000 and 2019.</p><p>
 <aside class="recommended pull pull--left sans-serif" data-label="Related">
  <a href="https://www.nature.com/news/investigating-journals-the-dark-side-of-publishing-1.12666" data-track="click" data-track-label="recommended article"><img class="recommended__image" alt="" src="//media.nature.com/w400/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_15541288.jpg"><h1 class="recommended__title serif">Investigating journals: The dark side of publishing</h1></a>
 </aside></p><p>More than half of these journals were in the social sciences and humanities, although life sciences, health sciences, physical sciences and mathematics were also represented. Eighty-eight of the journals were affiliated with a scholarly society or a research institution. The analysis also identified 900 journals that are still online but seem to have stopped publishing papers, so might be vulnerable to vanishing in the near future.</p><p>The study lays out a "compelling case" for the vulnerability of online journals, says Elizabeth Lightfoot, a librarian at Florida International University in Miami.</p><h2>Vanishing journals</h2><p>Journals can disappear from the Internet for a number of reasons, says Laakso. The publisher might stop paying to keep its publication’s webpage afloat, for example, or journals might be hosted on an online platform that belongs to an academic institution and is left behind when the site or server is updated.</p><p>Journals are supposed to be preserved in digital archives when this happens. Services such as the LOCKSS (Lots of Copies Keep Stuff Safe) Program, which was launched by Stanford Libraries in 1999, aim to ensure that publications remain available even when the publisher is no longer around. LOCKSS works by making multiple copies of content that is stored on the servers of participating libraries, who pay an annual fee to have their collections preserved. Similar initiatives, including CLOCKSS, Portico and the Public Knowledge Project’s Preservation Network (PKP PN), have emerged over the past two decades. These vary in cost and coverage: Some work with libraries, others with publishers — services such as PKP PN are free for journals that sign up. Tens of thousands of titles are currently curated in such preservation schemes. But, Laakso says, there are dozens of journals that fall through the cracks.</p><p>
 <aside class="recommended pull pull--left sans-serif" data-label="Related">
  <a href="https://www.nature.com/articles/d41586-018-06178-7" data-track="click" data-track-label="recommended article"><img class="recommended__image" alt="" src="//media.nature.com/w400/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_16099234.jpg"><h1 class="recommended__title serif">Radical open-access plan could spell end to journal subscriptions</h1></a>
 </aside></p><p>Pinning down whether a journal is truly unavailable online is a challenge, because there is no single database that tracks the activity of open-access journals, says Lisa Matthias, one of the authors of the study and a PhD student at the Free University of Berlin. Databases such as the Directory of Open Access Journals (DOAJ) don’t keep track of journals that no longer publish — and journals that cease publishing or stop maintaining their presence on the web usually do so silently.</p><p>To find out how many journals had vanished, the team manually collected historical data from several lists of titles, including the DOAJ, Ulrichsweb and Scopus. Then they checked to see if any of the titles they identified were listed on the Keepers Registry, which keeps track of journals that are enrolled into digital preservation schemes. Finally, they went to the Internet Archive’s Wayback Machine to access snapshots of now-offline journals’ websites to see when they had last published, and when the content was last available on the Internet. Journals were considered “vanished” if less than 50% of their content was still freely available online (the researchers acknowledge that some journals could exist in print form or behind a paywall).</p><p>The majority of the 176 vanished journals had disappeared within 5 years of becoming inactive — the point at which they stopped publishing papers. Around one-third of them disappeared within one year of the last publication. The researchers used this ‘life cycle’ to estimate that another 900 inactive open-access journalscould be at risk of vanishing.</p><h2>Preserving the literature</h2><p>Subscription journals were not included in the study, Laakso says, because paywalls mean that they would have had to have used a different method to collect the data. He adds that because of this and other limitations, the study probably underestimates the number of journals that have disappeared. “It’s really hard to pin down when something doesn't absolutely exist, but we tried our best,” Laakso says. “We hope that there will be more refined and automatic ways to detect these in the future.”</p><p>
 <aside class="recommended pull pull--left sans-serif" data-label="Related">
  <a href="https://www.nature.com/articles/d41586-019-02038-0" data-track="click" data-track-label="recommended article"><img class="recommended__image" alt="" src="//media.nature.com/w400/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_16870448.jpg"><h1 class="recommended__title serif">India culls hundreds more ‘dubious’ journals from government approved list</h1></a>
 </aside></p><p>Thib Guicherd-Callin, the acting manager of the LOCKSS Program, says it’s not surprising that there are journals that aren't captured by existing preservation services. Although many groups have used the open-source LOCKSS software, efforts to launch digital preservation initiatives are still “woefully underfunded”, he adds. “The desire to preserve these at-risk works is there,” he adds, but few institutions are investing the resources necessary to identify these publications and make sure they’re included in a digital preservation scheme.</p><p>Matthias says that the responsibility for ensuring inactive journals don’t disappear should be shared between publishers, authors, librarians and preservation services. Lightfoot agrees that a coordinated and collaborative effort is necessary. However, she adds, “the twin challenges of what that effort might look like and who would fund it make the pathway forward murky at best”.</p>
                    </div>
                
                    <div class="emphasis">doi: <a href="https://doi.org/10.1038/d41586-020-02610-z">https://doi.org/10.1038/d41586-020-02610-z</a></div>
                <div class="anchor-link mt40" data-toggle="anchor-links"></div>
                <div id="references" class="references" data-toggle="anchor-links-section" data-label="References" data-concertina="true">
                    <section aria-labelledby="Bib1"><div class="serif article-section js-article-section cleared clear" id="Bib1-section"><h2 class="js-section-title section-title strong position-relative tighten-line-height background-gray-light pt20 pb6 pl0 pr20 standard-space-below small-space-above mq640-pt10 mq640-pb10 mq640-pl20 mq640-mt0 mq640-ml-20 mq640-mr-20 extend-left" id="Bib1">References</h2><div class="pl20 mq875-pl0 js-collapsible-section" id="Bib1-content"><div data-container-section="references"><ol class="clean-list ma0 standard-space-below indented-list" data-test="references-list"><li class="small-space-below border-gray-medium border-bottom-1 position-relative js-ref-item" itemprop="citation" itemscope="itemscope" itemtype="http://schema.org/Article" data-test="citation"><span class="indented-counter serif h2 tighten-line-height text-right position-absolute grade-c-hide">1.</span><p class="tiny-space-below" id="ref-CR1">Laakso, M., Matthias, L. &amp; Jahn, N. Preprint at <a href="https://arxiv.org/abs/2008.11933">https://arxiv.org/abs/2008.11933</a> (2020).</p><ul class="js-ref-links clean-list cleared strong sans-serif text13 hide-print small-space-below"><li class="pin-right"><ul class="clean-list ma0"></ul></li></ul></li></ol><p class="hide-print text-right"><a href="/articles/d41586-020-02610-z-references.ris" class="text14 sans-serif strong" data-track="click" data-track-action="download citation references" data-track-label="link">Download references</a></p></div></div></div></section>
                </div>
                
                    
                
                


    <div class="nature-briefing nature-briefing-box mt0 cleared hide-print" data-component-id="nature-briefing-box" data-track="in-view" data-track-action="in-view" data-track-category="nature briefing" data-track-label="inPage box visible">
        <div class="nature-briefing-box__header pa20">
            <h1 class="h2 strong pb10 extra-tight-line-height">Nature Briefing</h1>
            <p class="nature-briefing-box__standfirst mb0 sans-serif tighten-line-height">An essential round-up of science news, opinion and analysis, delivered to your inbox every weekday.</p>
        </div>
        <form action="/briefing/signup/formfeedback" method="post" class="nature-briefing-box__form pa20" data-location="box" data-track="submit" data-track-action="transmit-form">
            <input id="briefing-box-signup-form-inPage-input-track-originReferralPoint" type="hidden" name="track_originReferralPoint" value="DirectEmailBox-inPage">
            <input id="briefing-box-signup-form-inPage-input-track-formType" type="hidden" name="track_formType" value="DirectEmailBox">
            <label class="nature-briefing-box__input-label block strong" for="box-inPage-EmailAddressInput">Email address</label>
            <input class="nature-briefing-box__input-input block border-all-1 equalize-line-height pa10 mb10 box-sizing grid-12" type="email" id="box-inPage-EmailAddressInput" name="email" value="" placeholder="e.g. jo.smith@university.ac.uk" required="true" aria-required="true" data-test-element="briefing-box-email-input">

            <div class="mb20 position-relative" role="group">
                <input class="nature-briefing-box__checkbox-checkbox" id="gdpr-briefing-box-inPage-checkbox" type="checkbox" name="gdpr" value="1" data-test-element="briefing-box-gdpr-checkbox" required>
                <label class="nature-briefing-box__checkbox-label tighten-line-height" for="gdpr-briefing-box-inPage-checkbox">Yes! Sign me up to receive the daily <em>Nature Briefing</em> email. I agree my information will be processed in accordance with the <em>Nature</em> and Springer Nature Limited <a href="https://www.nature.com/info/privacy">Privacy Policy</a>.</label>
            </div>

            <button type="submit" class="nature-briefing-box__submit-button c-btn--squared" data-test-element="briefing-box-signup-button">Sign up</button>

        </form>
    </div>




            </div>

            <aside class="article__aside align-right">
                <div class="related-content shrink--aside hide-print">
                        
                            <h3 class="aside__title sans-serif">Related Articles</h3>
                            <ul class="ma0 clean-list">
                                
                                    <li class="article-item article-item--rc cleared">
                                        <h3 class="article-item__title serif">
                                            <a href="https://www.nature.com/articles/d41586-018-06178-7" data-track="click"
                                               data-track-label="related article (rank:0)">
                                                
                                                    <img class="figure__image" data-src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_16099234.jpg"
                                                         alt="Radical open-access plan could spell end to journal subscriptions">
                                                    <noscript>
                                                        <img class="figure__image figure--no-js"
                                                             src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_16099234.jpg"
                                                             alt="Radical open-access plan could spell end to journal subscriptions">
                                                    </noscript>
                                                
                                                Radical open-access plan could spell end to journal subscriptions
                                            </a>
                                        </h3>
                                    </li>
                                
                                    <li class="article-item article-item--rc cleared">
                                        <h3 class="article-item__title serif">
                                            <a href="https://www.nature.com/news/investigating-journals-the-dark-side-of-publishing-1.12666" data-track="click"
                                               data-track-label="related article (rank:1)">
                                                
                                                    <img class="figure__image" data-src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_15541288.jpg"
                                                         alt="Investigating journals: The dark side of publishing">
                                                    <noscript>
                                                        <img class="figure__image figure--no-js"
                                                             src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_15541288.jpg"
                                                             alt="Investigating journals: The dark side of publishing">
                                                    </noscript>
                                                
                                                Investigating journals: The dark side of publishing
                                            </a>
                                        </h3>
                                    </li>
                                
                                    <li class="article-item article-item--rc cleared">
                                        <h3 class="article-item__title serif">
                                            <a href="https://www.nature.com/articles/d41586-020-01066-5" data-track="click"
                                               data-track-label="related article (rank:2)">
                                                
                                                    <img class="figure__image" data-src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_18030798.jpg"
                                                         alt="Nature to join open-access Plan S, publisher says">
                                                    <noscript>
                                                        <img class="figure__image figure--no-js"
                                                             src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_18030798.jpg"
                                                             alt="Nature to join open-access Plan S, publisher says">
                                                    </noscript>
                                                
                                                Nature to join open-access Plan S, publisher says
                                            </a>
                                        </h3>
                                    </li>
                                
                                    <li class="article-item article-item--rc cleared">
                                        <h3 class="article-item__title serif">
                                            <a href="https://www.nature.com/articles/d41586-018-07557-w" data-track="click"
                                               data-track-label="related article (rank:3)">
                                                
                                                    <img class="figure__image" data-src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_16355294.jpg"
                                                         alt="Funders flesh out details of Europe’s bold open-access plan">
                                                    <noscript>
                                                        <img class="figure__image figure--no-js"
                                                             src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_16355294.jpg"
                                                             alt="Funders flesh out details of Europe’s bold open-access plan">
                                                    </noscript>
                                                
                                                Funders flesh out details of Europe’s bold open-access plan
                                            </a>
                                        </h3>
                                    </li>
                                
                                    <li class="article-item article-item--rc cleared">
                                        <h3 class="article-item__title serif">
                                            <a href="https://www.nature.com/articles/d41586-018-07245-9" data-track="click"
                                               data-track-label="related article (rank:4)">
                                                
                                                    <img class="figure__image" data-src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_17334214.jpg"
                                                         alt="AI peer reviewers unleashed to ease publishing grind">
                                                    <noscript>
                                                        <img class="figure__image figure--no-js"
                                                             src="//media.nature.com/lw100/magazine-assets/d41586-020-02610-z/d41586-020-02610-z_17334214.jpg"
                                                             alt="AI peer reviewers unleashed to ease publishing grind">
                                                    </noscript>
                                                
                                                AI peer reviewers unleashed to ease publishing grind
                                            </a>
                                        </h3>
                                    </li>
                                
                                    <li class="article-item article-item--rc cleared">
                                        <h3 class="article-item__title serif">
                                            <a href="https://www.nature.com/news/open-access-the-true-cost-of-science-publishing-1.12676" data-track="click"
                                               data-track-label="related article (rank:5)">
                                                
                                                The true cost of science publishing
                                            </a>
                                        </h3>
                                    </li>
                                
                            </ul>
                </div>
                
                    <div class="article__subjects bordered-container shrink--aside hide-print">
                        <h3 class="aside__title sans-serif">Subjects</h3>
                        <ul class="ma0 subject-list cleared clean-list inline-list">
                            
                                <li class="subject"><a href="/subjects/publishing" data-track="click"
                                                       data-track-label="subject (rank:0)">Publishing</a>
                                </li>
                            
                        </ul>
                    </div>
                
                
    
<div id="div-gpt-ad-right-2"
     class="div-gpt-ad medium-rectangle advert js-ad text-center hide-print grade-c-hide"
     data-gpt-unitpath="/285/nature.com/article"
     data-gpt-sizes="300x250"
     data-gpt-targeting="pos=right;artid=/articles/d41586-020-02610-z;path=/articles/d41586-020-02610-z"
     data-ad-type="right"
     >
    <noscript>
        <a href="//pubads.g.doubleclick.net/gampad/jump?iu=/285/nature.com/article&amp;sz=300x250&amp;c=1791348774&amp;t=pos%3Dright%26artid%3D/articles/d41586-020-02610-z">
            <img data-test="gpt-advert-fallback-img"
                 src="//pubads.g.doubleclick.net/gampad/ad?iu=/285/nature.com/article&amp;sz=300x250&amp;c=1791348774&amp;t=pos%3Dright%26artid%3D/articles/d41586-020-02610-z"
                 alt="Advertisement"
                 width="300"
                 height="250"/>
        </a>
    </noscript>
</div>


                <div class="nature-briefing--sidebar bordered-container shrink--aside hide-print">
    

    <div class="nature-briefing nature-briefing-box mt0 cleared hide-print" data-component-id="nature-briefing-box" data-track="in-view" data-track-action="in-view" data-track-category="nature briefing" data-track-label="sidebar box visible">
        <div class="nature-briefing-box__header pa20">
            <h1 class="h2 strong pb10 extra-tight-line-height">Sign up to Nature Briefing</h1>
            <p class="nature-briefing-box__standfirst mb0 sans-serif tighten-line-height">An essential round-up of science news, opinion and analysis, delivered to your inbox every weekday.</p>
        </div>
        <form action="/briefing/signup/formfeedback" method="post" class="nature-briefing-box__form pa20" data-location="box" data-track="submit" data-track-action="transmit-form">
            <input id="briefing-box-signup-form-sidebar-input-track-originReferralPoint" type="hidden" name="track_originReferralPoint" value="DirectEmailBox-sidebar">
            <input id="briefing-box-signup-form-sidebar-input-track-formType" type="hidden" name="track_formType" value="DirectEmailBox">
            <label class="nature-briefing-box__input-label block strong" for="box-sidebar-EmailAddressInput">Email address</label>
            <input class="nature-briefing-box__input-input block border-all-1 equalize-line-height pa10 mb10 box-sizing grid-12" type="email" id="box-sidebar-EmailAddressInput" name="email" value="" placeholder="e.g. jo.smith@university.ac.uk" required="true" aria-required="true" data-test-element="briefing-box-email-input">

            <div class="mb20 position-relative" role="group">
                <input class="nature-briefing-box__checkbox-checkbox" id="gdpr-briefing-box-sidebar-checkbox" type="checkbox" name="gdpr" value="1" data-test-element="briefing-box-gdpr-checkbox" required>
                <label class="nature-briefing-box__checkbox-label tighten-line-height" for="gdpr-briefing-box-sidebar-checkbox">Yes! Sign me up to receive the daily <em>Nature Briefing</em> email. I agree my information will be processed in accordance with the <em>Nature</em> and Springer Nature Limited <a href="https://www.nature.com/info/privacy">Privacy Policy</a>.</label>
            </div>

            <button type="submit" class="nature-briefing-box__submit-button c-btn--squared" data-test-element="briefing-box-signup-button">Sign up</button>

        </form>
    </div>


</div>

            </aside>
        </div>
    </div>
    <div data-microformat-only="" itemscope="" itemprop="publisher" itemtype="https://schema.org/Organization">
        <meta content="Macmillan Publishers Limited, part of Springer Nature" itemprop="name"/>
    </div>
    <div data-microformat-only="" itemscope="" itemprop="author" itemtype="https://schema.org/Organization">
        <meta content="Nature Editorial" itemprop="name"/>
    </div>
    <img src="/platform/track/article/d41586-020-02610-z" width="1" height="1" alt="" class="visually-hidden"/>
</article>

        





<div class="c-site-messages message hide u-hide-print c-site-messages--nature-briefing c-site-messages--nature-briefing-email-variant c-site-messages--nature-briefing-redesign-2020 sans-serif"
data-component-id="nature-briefing-banner"
data-component-expirydays="30"
data-component-trigger-scroll-percentage="15"
data-track="in-view"
data-track-action="in-view"
data-track-category="nature briefing"
data-track-label="redesign banner visible">

    
    <div class="c-site-messages__banner-large">

        
<div class="c-site-messages__close-container ">
    <button class="c-site-messages__close"
        data-track="click"
        data-track-category="nature briefing"
        data-track-label="redesign banner dismiss">
        <span class="">
            <?xml version="1.0" encoding="UTF-8" standalone="no"?>
            <svg width="25px" height="25px" focusable="false" aria-hidden="true" viewBox="0 0 25 25" version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
                <title>Close banner</title>
                <defs></defs>
                <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd">
                    <rect opacity="0" x="0" y="0" width="25" height="25"></rect>
                    <path d="M6.29679575,16.2772478 C5.90020818,16.6738354 5.90240728,17.3100587 6.29617427,17.7038257 C6.69268654,18.100338 7.32864195,18.0973145 7.72275218,17.7032043 L12,13.4259564 L16.2772478,17.7032043 C16.6738354,18.0997918 17.3100587,18.0975927 17.7038257,17.7038257 C18.100338,17.3073135 18.0973145,16.671358 17.7032043,16.2772478 L13.4259564,12 L17.7032043,7.72275218 C18.0997918,7.32616461 18.0975927,6.68994127 17.7038257,6.29617427 C17.3073135,5.89966201 16.671358,5.90268552 16.2772478,6.29679575 L12,10.5740436 L7.72275218,6.29679575 C7.32616461,5.90020818 6.68994127,5.90240728 6.29617427,6.29617427 C5.89966201,6.69268654 5.90268552,7.32864195 6.29679575,7.72275218 L10.5740436,12 L6.29679575,16.2772478 Z" fill="#ffffff"></path>
                </g>
            </svg>
        </span>
        <span class="visually-hidden">Close</span>
    </button>
</div>


        <div class="c-site-messages__form-container">

        

            <div class="grid grid-12 last">
                <div class="grid grid-4">
                    <img alt="Nature Briefing" src="/static/images/logos/nature-briefing-logo-n150-white.d81c9da3ec.svg" width="250" height="40">
                    <p class="c-site-messages--nature-briefing__strapline extra-tight-line-height">Sign up for the <em>Nature Briefing</em> newsletter — what matters in science, free to your inbox daily.</p>
                </div>
                <div class="grid grid-8 last">
                    <form action="/briefing/signup/formfeedback" method="post" data-location="banner" data-track="submit" data-track-action="transmit-form">
                        <input id="briefing-banner-signup-form-input-track-originReferralPoint" type="hidden" name="track_originReferralPoint" value="DirectEmailBannerRedesign2020">
                        <input id="briefing-banner-signup-form-input-track-formType" type="hidden" name="track_formType" value="DirectEmailBanner">
                        <label class="nature-briefing-banner__email-label" for="banner-EmailAddressInput">Email address</label>

                        <div class="nature-briefing-banner__email-wrapper">
                            <input class="nature-briefing-banner__email-input box-sizing text14" type="email" id="banner-EmailAddressInput" name="email" value="" placeholder="e.g. jo.smith@university.ac.uk" required="true" aria-required="true" data-test-element="briefing-emailbanner-email-input">
                            <button type="submit" class="nature-briefing-banner__submit-button box-sizing text14" data-test-element="briefing-emailbanner-signup-button">Sign up</button>
                        </div>

                        <div class="nature-briefing-banner__checkbox-wrapper grid grid-12 last">
                            <input class="nature-briefing-banner__checkbox-checkbox" id="gdpr-briefing-banner-checkbox" type="checkbox" name="gdpr" value="1" data-test-element="briefing-emailbanner-gdpr-checkbox" required>
                            <label class="nature-briefing-banner__checkbox-label box-sizing text13 sans-serif block tighten-line-height" for="gdpr-briefing-banner-checkbox">I agree my information will be processed in accordance with the <em>Nature</em> and Springer Nature Limited <a href="https://www.nature.com/info/privacy">Privacy Policy</a>.</label>
                        </div>
                    </form>
                </div>
            </div>

        
        </div>

    </div>

    
    <div class="c-site-messages__banner-small">

        
<div class="c-site-messages__close-container ">
    <button class="c-site-messages__close"
        data-track="click"
        data-track-category="nature briefing"
        data-track-label="redesign banner dismiss">
        <span class="">
            <?xml version="1.0" encoding="UTF-8" standalone="no"?>
            <svg width="25px" height="25px" focusable="false" aria-hidden="true" viewBox="0 0 25 25" version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
                <title>Close banner</title>
                <defs></defs>
                <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd">
                    <rect opacity="0" x="0" y="0" width="25" height="25"></rect>
                    <path d="M6.29679575,16.2772478 C5.90020818,16.6738354 5.90240728,17.3100587 6.29617427,17.7038257 C6.69268654,18.100338 7.32864195,18.0973145 7.72275218,17.7032043 L12,13.4259564 L16.2772478,17.7032043 C16.6738354,18.0997918 17.3100587,18.0975927 17.7038257,17.7038257 C18.100338,17.3073135 18.0973145,16.671358 17.7032043,16.2772478 L13.4259564,12 L17.7032043,7.72275218 C18.0997918,7.32616461 18.0975927,6.68994127 17.7038257,6.29617427 C17.3073135,5.89966201 16.671358,5.90268552 16.2772478,6.29679575 L12,10.5740436 L7.72275218,6.29679575 C7.32616461,5.90020818 6.68994127,5.90240728 6.29617427,6.29617427 C5.89966201,6.69268654 5.90268552,7.32864195 6.29679575,7.72275218 L10.5740436,12 L6.29679575,16.2772478 Z" fill="#ffffff"></path>
                </g>
            </svg>
        </span>
        <span class="visually-hidden">Close</span>
    </button>
</div>


        <div class="c-site-messages__content text14">
            <span class="c-site-messages--nature-briefing__strapline strong serif">Get the most important science stories of the day, free in your inbox.</span>
            <a class="nature-briefing__link text14 sans-serif"
                data-track="click"
                data-track-category="nature briefing"
                data-track-label="redesign banner CTA to site"
                data-test-element="briefing-banner-link"
                target="_blank"
                rel="noreferrer noopener"
                href="/briefing/signup/?origin=Nature&amp;originReferralPoint=EmailBanner">Sign up for Nature Briefing
            </a>
        </div>

    </div>

</div>

    </section>
</div>
    <script>
        window.onload = function () {
            Array.prototype.slice.call(document.querySelectorAll(".magazine-infographic > iframe"))
                    .forEach(function (element) {
                        function listener(event) {
                            if (event.data.height) {
                                if (element.id === event.data.requestData.id) {
                                    element.setAttribute("height", event.data.height)
                                }
                            }
                        }

                        window.addEventListener("message", listener);
                        element.contentWindow.postMessage({name: "getHeight", id: element.id}, "*");
                    });
        }
    </script>
    <script>
        var linkEl = document.querySelector('.js-ctm');
        if (linkEl && window.matchMedia && window.matchMedia(linkEl.media).matches) {
            var fragment = document.createDocumentFragment();
            var polyfillScript = document.createElement('script');
            var header150Script = null;
            var appScript = document.createElement('script');
            var sharedEs6Script =  document.createElement('script');

            polyfillScript.src = 'https://cdn.polyfill.io/v2/polyfill.min.js?features=default,IntersectionObserver,Array.prototype.includes,Promise';
            polyfillScript.async = false;
            fragment.appendChild(polyfillScript);

            appScript.src = '/static/js/magazine/magazine-mosaic.71d8740808.js';
            appScript.async = false;
            fragment.appendChild(appScript);

            sharedEs6Script.src = '/static/js/shared-es6-bundle.c83ed51f05.js';
            sharedEs6Script.async = false;
            fragment.appendChild(sharedEs6Script);

            header150Script = document.createElement('script');
            header150Script.src = '/static/js/header-150-bundle.aaea96385f.js';
            header150Script.async = false;
            fragment.appendChild(header150Script);

            document.body.appendChild(fragment);
        }
    </script>
    <script>
        var idp = {
            hasNatureUserProof: function (hasProof) {
                if (!hasProof) {
                    document.getElementById("my-account").setAttribute("style", "display: none;");
                    document.getElementById("login-button").setAttribute("style", "");
                }
            }
        }
    </script>
    <script src="https://verify.nature.com/verify/nature.min.js"></script>
    <noscript>
        <img src="https://verify.nature.com/verify/nature.png" alt="" width="0" height="0"/>
    </noscript>
    
        
    
        <nav class="u-hide-print c-header-expander" aria-labelledby="Explore-our-content" data-test="Explore-our-content" id="explore" data-track-component="nature-150-split-header">
            <div class="c-header-expander__container">
                <div class="c-header-expander__keyline">
                    <h2 id="Explore-our-content" class="c-header-expander__heading u-js-hide">Explore our content</h2>
                    <ul class="c-header-expander__list">
                        
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/nature/research"
                                       data-track="click"
                                       data-track-action="research"
                                       data-track-label="link">
                                        Research
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/news"
                                       data-track="click"
                                       data-track-action="news"
                                       data-track-label="link">
                                        News
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/opinion"
                                       data-track="click"
                                       data-track-action="opinion"
                                       data-track-label="link">
                                        Opinion
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/research-analysis"
                                       data-track="click"
                                       data-track-action="research analysis"
                                       data-track-label="link">
                                        Research Analysis
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/careers"
                                       data-track="click"
                                       data-track-action="careers"
                                       data-track-label="link">
                                        Careers
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/books-culture"
                                       data-track="click"
                                       data-track-action="books and culture"
                                       data-track-label="link">
                                        Books and Culture
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/nature/podcast"
                                       data-track="click"
                                       data-track-action="podcasts"
                                       data-track-label="link">
                                        Podcasts
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/nature/videoarchive"
                                       data-track="click"
                                       data-track-action="videos"
                                       data-track-label="link">
                                        Videos
                                    </a>
                                </li>
                            
                        
                        
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/nature/current-issue"
                                       data-track="click"
                                       data-track-action="current issue"
                                       data-track-label="link">
                                        Current Issue
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/nature/browse-issues"
                                       data-track="click"
                                       data-track-action="browse issues"
                                       data-track-label="link">
                                        Browse Issues
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/nature/articles"
                                       data-track="click"
                                       data-track-action="browse articles"
                                       data-track-label="link">
                                        Browse Articles
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/nature/collections"
                                       data-track="click"
                                       data-track-action="browse collections"
                                       data-track-label="link">
                                        Browse Collections
                                    </a>
                                </li>
                            
                                <li class="c-header-expander__item">
                                    <a class="c-header-expander__link"
                                       href="/nature/browse-subjects"
                                       data-track="click"
                                       data-track-action="browse subjects"
                                       data-track-label="link">
                                        Browse Subjects
                                    </a>
                                </li>
                            
                        
                        
                            <li class="c-header-expander__item c-header-expander__item--keyline">
                                <a class="c-header-expander__link"
                                   href="https://www.nature.com/my-account/alerts/subscribe-journal?list-id&#x3D;1"
                                   data-track="click"
                                   data-track-action="Sign up for alerts"
                                   data-track-label="link">Sign up for alerts<svg role="img" aria-hidden="true" focusable="false" height="18" viewBox="0 0 18 18" width="18" xmlns="http://www.w3.org/2000/svg"><path d="m4 10h2.5c.27614237 0 .5.2238576.5.5s-.22385763.5-.5.5h-3.08578644l-1.12132034 1.1213203c-.18753638.1875364-.29289322.4418903-.29289322.7071068v.1715729h14v-.1715729c0-.2652165-.1053568-.5195704-.2928932-.7071068l-1.7071068-1.7071067v-3.4142136c0-2.76142375-2.2385763-5-5-5-2.76142375 0-5 2.23857625-5 5zm3 4c0 1.1045695.8954305 2 2 2s2-.8954305 2-2zm-5 0c-.55228475 0-1-.4477153-1-1v-.1715729c0-.530433.21071368-1.0391408.58578644-1.4142135l1.41421356-1.4142136v-3c0-3.3137085 2.6862915-6 6-6s6 2.6862915 6 6v3l1.4142136 1.4142136c.3750727.3750727.5857864.8837805.5857864 1.4142135v.1715729c0 .5522847-.4477153 1-1 1h-4c0 1.6568542-1.3431458 3-3 3-1.65685425 0-3-1.3431458-3-3z" fill="#fff"/></svg>
                                </a>
                            </li>
                        
                    </ul>
                </div>
            </div>
        </nav>
    

    
        <nav class="u-hide-print c-header-expander" aria-labelledby="Journal-information" id="journal-info" data-track-component="nature-150-split-header">
            <div class="c-header-expander__container">
                <div class="c-header-expander__keyline">
                    <h2 id="Journal-information" class="c-header-expander__heading u-js-hide">Journal information</h2>
                    <ul class="c-header-expander__list">
                        
                            <li class="c-header-expander__item">
                                <a class="c-header-expander__link"
                                   href="/nature/about"
                                   data-track="click"
                                   data-track-action="about the journal"
                                   data-track-label="link">
                                    About the Journal
                                </a>
                            </li>
                        
                            <li class="c-header-expander__item">
                                <a class="c-header-expander__link"
                                   href="/nature/for-authors"
                                   data-track="click"
                                   data-track-action="for authors"
                                   data-track-label="link">
                                    For Authors
                                </a>
                            </li>
                        
                            <li class="c-header-expander__item">
                                <a class="c-header-expander__link"
                                   href="/nature/for-referees"
                                   data-track="click"
                                   data-track-action="for referees"
                                   data-track-label="link">
                                    For Referees
                                </a>
                            </li>
                        
                            <li class="c-header-expander__item">
                                <a class="c-header-expander__link"
                                   href="/nature/awards"
                                   data-track="click"
                                   data-track-action="awards"
                                   data-track-label="link">
                                    Awards
                                </a>
                            </li>
                        
                            <li class="c-header-expander__item">
                                <a class="c-header-expander__link"
                                   href="/nature/subscribe"
                                   data-track="click"
                                   data-track-action="subscribe"
                                   data-track-label="link">
                                    Subscribe
                                </a>
                            </li>
                        
                        
                            <li class="c-header-expander__item c-header-expander__item--keyline">
                                <a class="c-header-expander__link"
                                   href="http://mts-nature.nature.com/"
                                   data-track="click"
                                   data-track-action="Submit manuscript"
                                   data-track-label="link">Submit manuscript<svg role="img" aria-hidden="true" focusable="false" height="18" viewBox="0 0 18 18" width="18" xmlns="http://www.w3.org/2000/svg"><path d="m15 0c1.1045695 0 2 .8954305 2 2v5.5c0 .27614237-.2238576.5-.5.5s-.5-.22385763-.5-.5v-5.5c0-.51283584-.3860402-.93550716-.8833789-.99327227l-.1166211-.00672773h-9v3c0 1.1045695-.8954305 2-2 2h-3v10c0 .5128358.38604019.9355072.88337887.9932723l.11662113.0067277h7.5c.27614237 0 .5.2238576.5.5s-.22385763.5-.5.5h-7.5c-1.1045695 0-2-.8954305-2-2v-10.17157288c0-.53043297.21071368-1.0391408.58578644-1.41421356l3.82842712-3.82842712c.37507276-.37507276.88378059-.58578644 1.41421356-.58578644zm-.5442863 8.18867991 3.3545404 3.35454039c.2508994.2508994.2538696.6596433.0035959.909917-.2429543.2429542-.6561449.2462671-.9065387-.0089489l-2.2609825-2.3045251.0010427 7.2231989c0 .3569916-.2898381.6371378-.6473715.6371378-.3470771 0-.6473715-.2852563-.6473715-.6371378l-.0010428-7.2231995-2.2611222 2.3046654c-.2531661.2580415-.6562868.2592444-.9065605.0089707-.24295423-.2429542-.24865597-.6576651.0036132-.9099343l3.3546673-3.35466731c.2509089-.25090888.6612706-.25227691.9135302-.00001728zm-.9557137-3.18867991c.2761424 0 .5.22385763.5.5s-.2238576.5-.5.5h-6c-.27614237 0-.5-.22385763-.5-.5s.22385763-.5.5-.5zm-8.5-3.587-3.587 3.587h2.587c.55228475 0 1-.44771525 1-1zm8.5 1.587c.2761424 0 .5.22385763.5.5s-.2238576.5-.5.5h-6c-.27614237 0-.5-.22385763-.5-.5s.22385763-.5.5-.5z" fill="#fff"/></svg>
                                </a>
                            </li>
                        
                    </ul>
                </div>
            </div>
        </nav>
    




    <div id="search-menu" class="c-header-expander c-header-expander--tray u-hide-print" data-track-component="nature-150-split-header">
        <div class="c-header-expander__container">
            <h2 class="u-visually-hidden">Search</h2>
            <div data-test="inline-search">
                <div class="c-header-expander__keyline u-mb-16">
                    <form action="/search"
                          method="get"
                          role="search"
                          class="c-header-expander__form"
                          autocomplete="off"
                          data-dynamic-track-label
                          data-track="submit" data-track-action="search" data-track-label="form">
                        <label class="c-header-expander__heading" for="keywords">Article Search</label>
                        <div class="c-form-field u-display-flex">
                            <input type="text"
                                   class="c-form-field__input u-flex-shrink"
                                   id="keywords"
                                   name="q"
                                   value=""
                                   placeholder="Search by keywords or author"
                                   data-test="search-keywords">
                            <button type="submit" class="c-button c-button--contrast u-flex-static u-ml-8" data-test="search-submit">Search</button>
                        </div>
                        <p class="u-ma-0">
                            <a href="/search/advanced"
                               data-track="click" data-track-action="advanced search" data-track-label="link">
                                Advanced search
                            </a>
                        </p>
                    </form>
                </div>
                <div class="c-header-expander__keyline">
                    <h3 class="c-header-expander__heading">Quick links</h3>
                    <ul class="u-list-reset">
                        <li class="u-display-inline-block u-mr-24"><a href="/subjects" data-track="click" data-track-action="explore articles by subject" data-track-label="link">Explore articles by subject</a></li>
                        <li class="u-display-inline-block u-mr-24"><a href="/naturecareers" data-track="click" data-track-action="find a job" data-track-label="link">Find a job</a></li>
                        <li class="u-display-inline-block u-mr-24"><a href="/authors/index.html" data-track="click" data-track-action="guide to authors" data-track-label="link">Guide to authors</a></li>
                        <li class="u-display-inline-block u-mr-24"><a href="/authors/editorial_policies/" data-track="click" data-track-action="editorial policies" data-track-label="link">Editorial policies</a></li>
                    </ul>
                </div>
            </div>
        </div>
    </div>




<footer role="contentinfo" class="composite-layer">
    <div class="u-mt-16 u-mb-16">
    <div class="u-container">
        <div class="u-display-flex u-flex-wrap u-justify-content-space-between">
            <p class="c-meta u-ma-0 u-mr-24">
    
</p>

            <p class="c-meta u-ma-0">
                <span aria-level="2" class="c-meta__item" itemprop="name">
                    Nature
                </span>
                <span class="c-meta__item">
                    <abbr title="International Standard Serial Number">ISSN</abbr> <span itemprop="issn">1476-4687</span> (online)
                </span>
            </p>
        </div>
    </div>
</div>


    <div itemscope itemtype="http://schema.org/Periodical">
        <meta itemprop="publisher" content="Springer Nature">
        <div class="c-footer">
            <div class="u-container">
                <div class="u-hide-print" data-track-component="footer">
    <h2 aria-level="2" class="u-visually-hidden">nature.com sitemap</h2>
    <div class="c-footer__header">
        <div class="c-footer__logo">
            <img alt="Nature Research" src="/static/images/logos/nature research-white-150.f4acf77e0c.svg" loading="lazy" width="200" height="26">
        </div>
        <ul class="c-menu c-menu--inherit u-mr-32">
            <li class="c-menu__item"><a class="c-menu__link" href="https://www.nature.com/npg_/company_info/index.html" data-track="click" data-track-action="about us" data-track-label="link">About us</a></li>
            <li class="c-menu__item"><a class="c-menu__link" href="https://www.nature.com/npg_/press_room/press_releases.html" data-track="click" data-track-action="press releases" data-track-label="link">Press releases</a></li>
            <li class="c-menu__item"><a class="c-menu__link" href="https://press.nature.com/" data-track="click" data-track-action="press office" data-track-label="link">Press office</a></li>
            <li class="c-menu__item"><a class="c-menu__link" href="https://support.nature.com/support/home" data-track="click" data-track-action="contact us" data-track-label="link">Contact us</a></li>
        </ul>
        <ul class="c-menu c-menu--inherit">
            <li class="c-menu__item">
                <a class="c-menu__link" href="https://www.facebook.com/nature/" aria-label="Nature on Facebook" data-track="click" data-track-action="facebook" data-track-label="link">
                    <svg class="u-icon u-mt-2 u-mb-2" role="img" aria-hidden="true" focusable="false" xmlns="http://www.w3.org/2000/svg" width="16" height="16" viewBox="0 0 20 20"><path d="M2.5 20C1.1 20 0 18.9 0 17.5v-15C0 1.1 1.1 0 2.5 0h15C18.9 0 20 1.1 20 2.5v15c0 1.4-1.1 2.5-2.5 2.5h-3.7v-7.7h2.6l.4-3h-3v-2c0-.9.2-1.5 1.5-1.5h1.6V3.1c-.3 0-1.2-.1-2.3-.1-2.3 0-3.9 1.4-3.9 4v2.2H8.1v3h2.6V20H2.5z"/></svg>
                </a>
            </li>
            <li class="c-menu__item">
                <a class="c-menu__link" href="https://twitter.com/nresearchnews?lang=en" aria-label="Nature on Twitter" data-track="click" data-track-action="twitter" data-track-label="link">
                    <svg class="u-icon" role="img" aria-hidden="true" focusable="false" xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 20 20"><path d="M17.6 4.1c.8-.5 1.5-1.4 1.8-2.4-.8.5-1.7.9-2.6 1-.7-.8-1.8-1.4-3-1.4-2.3 0-4.1 1.9-4.1 4.3 0 .3 0 .7.1 1-3.4 0-6.4-1.8-8.4-4.4C1 2.9.8 3.6.8 4.4c0 1.5.7 2.8 1.8 3.6C2 8 1.4 7.8.8 7.5v.1c0 2.1 1.4 3.8 3.3 4.2-.3.1-.7.2-1.1.2-.3 0-.5 0-.8-.1.5 1.7 2 3 3.8 3-1.3 1.1-3.1 1.8-5 1.8-.3 0-.7 0-1-.1 1.8 1.2 4 1.9 6.3 1.9C13.8 18.6 18 12 18 6.3v-.6c.8-.6 1.5-1.4 2-2.2-.7.3-1.5.5-2.4.6z"/></svg>
                </a>
            </li>
            <li class="c-menu__item">
                <a class="c-menu__link" href="https://www.youtube.com/channel/UCvCLdSgYdSTpWcOgEJgi-ng" aria-label="Nature on YouTube" data-track="click" data-track-action="youtube" data-track-label="link">
                    <svg class="u-icon" role="img" aria-hidden="true" focusable="false" xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 20 20"><path d="M7.9 12.6V6.9l5.4 2.8c0 .1-5.4 2.9-5.4 2.9zM19.8 6s-.2-1.4-.8-2c-.8-.8-1.6-.8-2-.9-2.8-.2-7-.2-7-.2s-4.2 0-7 .2c-.4 0-1.2 0-2 .9-.6.6-.8 2-.8 2S0 7.6 0 9.2v1.5c0 1.7.2 3.3.2 3.3s.2 1.4.8 2c.8.8 1.8.8 2.2.9 1.6.1 6.8.2 6.8.2s4.2 0 7-.2c.4 0 1.2-.1 2-.9.6-.6.8-2 .8-2s.2-1.6.2-3.3V9.2c0-1.6-.2-3.2-.2-3.2z"/></svg>
                </a>
            </li>
        </ul>
    </div>

    <div class="c-footer__grid">
        <div class="c-footer__group">
            <h3 class="c-footer__heading">Discover content</h3>
            <ul class="c-footer__list">
                <li class="c-footer__item"><a href="https://www.nature.com/siteindex" data-track="click" data-track-action="journals a-z" data-track-label="link">Journals A-Z</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/subjects/" data-track="click" data-track-action="article by subject" data-track-label="link">Articles by subject</a></li>
                <li class="c-footer__item"><a href="https://nano.nature.com/" data-track="click" data-track-action="nano" data-track-label="link">Nano</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/protocolexchange/" data-track="click" data-track-action="protocol exchange" data-track-label="link">Protocol Exchange</a></li>
                <li class="c-footer__item"><a href="https://www.natureindex.com/" data-track="click" data-track-action="nature index" data-track-label="link">Nature Index</a></li>
            </ul>
        </div>

        <div class="c-footer__group">
            <h3 class="c-footer__heading">Publish with us</h3>
            <ul class="c-footer__list">
                <li class="c-footer__item"><a href="https://www.nature.com/authors/author_resources/index.html" data-track="click" data-track-action="guide to authors" data-track-label="link">Guide to Authors</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/authors/peer_review/" data-track="click" data-track-action="guide to referees" data-track-label="link">Guide to Referees</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/authors/editorial_policies/" data-track="click" data-track-action="editorial policies" data-track-label="link">Editorial policies</a></li>
                <li class="c-footer__item"><a href="http://www.nature.com/openresearch/publishing-with-npg/" data-track="click" data-track-action="open access" data-track-label="link">Open access</a></li>
                <li ><a href="https://www.nature.com/reprints/" data-track="click" data-track-action="reprints and permissions" data-track-label="link">Reprints &amp; permissions</a></li>
            </ul>
        </div>

        <div class="c-footer__group">
            <h3 class="c-footer__heading">Researcher services</h3>
            <ul class="c-footer__list">
                <li class="c-footer__item"><a href="https://www.springernature.com/gp/authors/research-data" data-track="click" data-track-action="data research service" data-track-label="link">Research data</a></li>
                <li class="c-footer__item"><a href="https://authorservices.springernature.com/go/nr" data-track="click" data-track-action="language editing" data-track-label="link">Language editing</a></li>
                <li class="c-footer__item"><a href="https://authorservices.springernature.com/scientific-editing/" data-track="click" data-track-action="scientific editing" data-track-label="link">Scientific editing</a></li>
                <li class="c-footer__item"><a href="https://masterclasses.nature.com/" data-track="click" data-track-action="nature masterclasses" data-track-label="link">Nature Masterclasses</a></li>
                <li class="c-footer__item"><a href="https://partnerships.nature.com/product/researcher-training/" data-track="click" data-track-action="nature research academies" data-track-label="link">Nature Research Academies</a></li>
            </ul>
        </div>

        <div class="c-footer__group">
            <h3 class="c-footer__heading">Libraries &amp; institutions</h3>
            <ul class="c-footer__list">
                <li class="c-footer__item"><a href="https://www.springernature.com/gp/librarians/tools-services" data-track="click" data-track-action="librarian service and tools" data-track-label="link">Librarian service &amp; tools</a></li>
                <li class="c-footer__item"><a href="https://www.springernature.com/gp/librarians/manage-your-account/librarianportal" data-track="click" data-track-action="librarian portal" data-track-label="link">Librarian portal</a></li>
                <li class="c-footer__item"><a href="http://www.nature.com/openresearch/about-open-access/information-for-institutions/" data-track="click" data-track-action="open research" data-track-label="link">Open research</a></li>
            </ul>
        </div>

        <div class="c-footer__group">
            <h3 class="c-footer__heading">Advertising &amp; partnerships</h3>
            <ul class="c-footer__list">
                <li class="c-footer__item"><a href="https://partnerships.nature.com/product/digital-advertising/" data-track="click" data-track-action="advertising" data-track-label="link">Advertising</a></li>
                <li class="c-footer__item"><a href="https://partnerships.nature.com/" data-track="click" data-track-action="partnerships and services" data-track-label="link">Partnerships &amp; Services</a></li>
                <li class="c-footer__item"><a href="https://partnerships.nature.com/media-kits/" data-track="click" data-track-action="media kits" data-track-label="link">Media kits</a></li>
                <li class="c-footer__item"><a href="https://partnerships.nature.com/product/branded-content-native-advertising/" data-track-action="branded content" data-track-label="link">Branded content</a></li>
            </ul>
        </div>

        <div class="c-footer__group">
            <h3 class="c-footer__heading">Career development</h3>
            <ul class="c-footer__list">
                <li class="c-footer__item"><a href="https://www.nature.com/naturecareers" data-track="click" data-track-action="nature careers" data-track-label="link">Nature Careers</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/natureconferences/" data-track="click" data-track-action="nature conferences" data-track-label="link">Nature<span class="visually-hidden"> </span> Conferences</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/natureevents/" data-track="click" data-track-action="nature events" data-track-label="link">Nature<span class="visually-hidden"> </span> events</a></li>
            </ul>
        </div>

        <div class="c-footer__group">
            <h3 class="c-footer__heading">Regional websites</h3>
            <ul class="c-footer__list">
                <li class="c-footer__item"><a href="http://www.naturechina.com" data-track="click" data-track-action="nature china" data-track-label="link">Nature China</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/nindia" data-track="click" data-track-action="nature india" data-track-label="link">Nature India</a></li>
                <li class="c-footer__item"><a href="https://www.natureasia.com/ja-jp/" data-track="click" data-track-action="nature japan" data-track-label="link">Nature Japan</a></li>
                <li class="c-footer__item"><a href="https://www.natureasia.com/ko-kr/" data-track="click" data-track-action="nature korea" data-track-label="link">Nature Korea</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/nmiddleeast/" data-track="click" data-track-action="nature middle east" data-track-label="link">Nature Middle East</a></li>
            </ul>
        </div>

        <div class="c-footer__group">
            <h3 class="c-footer__heading">Legal &amp; Privacy</h3>
            <ul class="c-footer__list">
                <li class="c-footer__item"><a href="https://www.nature.com/info/privacy.html" data-track="click" data-track-action="privacy policy" data-track-label="link">Privacy Policy</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/info/cookies.html" data-track="click" data-track-action="use of cookies" data-track-label="link">Use of cookies</a></li>
                <li class="c-footer__item"><a class="optanon-toggle-display" href="javascript:;" data-track="click" data-track-action="manage cookies" data-track-label="link">Manage cookies/Do not sell my data</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/info/legal_notice.html" data-track="click" data-track-action="legal notice" data-track-label="link">Legal notice</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/info/accessibility_statement.html" data-track="click" data-track-action="accessibility statement" data-track-label="link">Accessibility statement</a></li>
                <li class="c-footer__item"><a href="https://www.nature.com/info/tandc.html" data-track="click" data-track-action="terms and conditions" data-track-label="link">Terms &amp; Conditions</a></li>
                <li class="c-footer__item"><a href="https://www.springernature.com/ccpa" data-track="click" data-track-action="california privacy statement" data-track-label="link">California Privacy Statement</a></li>
            </ul>
        </div>
    </div>
</div>


            </div>
        </div>
    </div>

    <div class="c-corporate-footer">
    <div class="u-container">
        <img src="/static/images/logos/sn-logo-white.ea63208b81.svg" alt="Springer Nature" loading="lazy" width="140" height="14"/>
        <p class="c-corporate-footer__legal" data-test="copyright">&copy; 2020 Springer Nature Limited</p>
    </div>
</div>

    
    <svg class="u-hide hide">
        <symbol id="global-icon-chevron-right" viewBox="0 0 16 16">
            <path d="M7.782 7L5.3 4.518c-.393-.392-.4-1.022-.02-1.403a1.001 1.001 0 011.417 0l4.176 4.177a1.001 1.001 0 010 1.416l-4.176 4.177a.991.991 0 01-1.4.016 1 1 0 01.003-1.42L7.782 9l1.013-.998z" fill-rule="evenodd"/>
        </symbol>
        <symbol id="global-icon-download" viewBox="0 0 16 16">
            <path d="M2 14c0-.556.449-1 1.002-1h9.996a.999.999 0 110 2H3.002A1.006 1.006 0 012 14zM9 2v6.8l2.482-2.482c.392-.392 1.022-.4 1.403-.02a1.001 1.001 0 010 1.417l-4.177 4.177a1.001 1.001 0 01-1.416 0L3.115 7.715a.991.991 0 01-.016-1.4 1 1 0 011.42.003L7 8.8V2c0-.55.444-.996 1-.996.552 0 1 .445 1 .996z" fill-rule="evenodd"/>
        </symbol>
        <symbol id="global-icon-email" viewBox="0 0 18 18">
            <path d="M1.995 2h14.01A2 2 0 0118 4.006v9.988A2 2 0 0116.005 16H1.995A2 2 0 010 13.994V4.006A2 2 0 011.995 2zM1 13.994A1 1 0 001.995 15h14.01A1 1 0 0017 13.994V4.006A1 1 0 0016.005 3H1.995A1 1 0 001 4.006zM9 11L2 7V5.557l7 4 7-4V7z" fill-rule="evenodd"/>
        </symbol>
        <symbol id="global-icon-institution" viewBox="0 0 18 18">
            <path d="M14 8a1 1 0 011 1v6h1.5a.5.5 0 01.5.5v.5h.5a.5.5 0 01.5.5V18H0v-1.5a.5.5 0 01.5-.5H1v-.5a.5.5 0 01.5-.5H3V9a1 1 0 112 0v6h8V9a1 1 0 011-1zM6 8l2 1v4l-2 1zm6 0v6l-2-1V9zM9.573.401l7.036 4.925A.92.92 0 0116.081 7H1.92a.92.92 0 01-.528-1.674L8.427.401a1 1 0 011.146 0zM9 2.441L5.345 5h7.31z" fill-rule="evenodd"/>
        </symbol>
        <symbol id="global-icon-search" viewBox="0 0 22 22">
            <path fill-rule="evenodd" d="M21.697 20.261a1.028 1.028 0 01.01 1.448 1.034 1.034 0 01-1.448-.01l-4.267-4.267A9.812 9.811 0 010 9.812a9.812 9.811 0 1117.43 6.182zM9.812 18.222A8.41 8.41 0 109.81 1.403a8.41 8.41 0 000 16.82z"/>
        </symbol>
        <symbol id="global-icon-info" viewBox="0 0 18 18">
            <path d="m9 0c4.9705627 0 9 4.02943725 9 9 0 4.9705627-4.0294373 9-9 9-4.97056275 0-9-4.0294373-9-9 0-4.97056275 4.02943725-9 9-9zm0 7h-1.5l-.11662113.00672773c-.49733868.05776511-.88337887.48043643-.88337887.99327227 0 .47338693.32893365.86994729.77070917.97358929l.1126697.01968298.11662113.00672773h.5v3h-.5l-.11662113.0067277c-.42082504.0488782-.76196299.3590206-.85696816.7639815l-.01968298.1126697-.00672773.1166211.00672773.1166211c.04887817.4208251.35902055.761963.76398144.8569682l.1126697.019683.11662113.0067277h3l.1166211-.0067277c.4973387-.0577651.8833789-.4804365.8833789-.9932723 0-.4733869-.3289337-.8699473-.7707092-.9735893l-.1126697-.019683-.1166211-.0067277h-.5v-4l-.00672773-.11662113c-.04887817-.42082504-.35902055-.76196299-.76398144-.85696816l-.1126697-.01968298zm0-3.25c-.69035594 0-1.25.55964406-1.25 1.25s.55964406 1.25 1.25 1.25 1.25-.55964406 1.25-1.25-.55964406-1.25-1.25-1.25z" fill-rule="evenodd"/>
        </symbol>
    </svg>

</footer>

    
</body>
</html>